What is Probasin promoter?

Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer. Cancer Res.

What is androgen receptor therapy?

Hormone therapy is also called androgen suppression therapy. The goal is to reduce levels of male hormones, called androgens, in the body, or to stop them from fueling prostate cancer cells. Androgens stimulate prostate cancer cells to grow. The main androgens in the body are testosterone and dihydrotestosterone (DHT).

What type of cancer is prostate cancer?

Almost all prostate cancers are adenocarcinomas. These cancers develop from the gland cells (the cells that make the prostate fluid that is added to the semen).

How effective is Casodex?

The efficacy and tolerability of Casodex, a new non-steroidal antiandrogen, were studied in 267 patients with advanced prostate cancer. All patients received Casodex, 50 mg daily, as monotherapy. The objective response rate was 55.5% and the subjective response rate was 56.1%.

What is androgen inhibitor drugs?

Androgen receptor inhibitors are used to slow down or stop the growth of cancer cells to treat prostate cancer. They work by inhibiting androgen hormones.

What is PSA level?

The PSA test is a blood test used primarily to screen for prostate cancer. The test measures the amount of prostate-specific antigen (PSA) in your blood. PSA is a protein produced by both cancerous and noncancerous tissue in the prostate, a small gland that sits below the bladder in males.

Is Casodex considered chemotherapy?

Official Answer. No, Casodex is not a form of chemotherapy, Casodex (bicalutamide) is an anti-androgen which is a type of hormone therapy used to treat prostate cancer. When you have cancer there are different options of cancer treatment including: hormone therapy.

What do androgen receptor blockers do?

A substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells, and in cells of some other tissues. Preventing this binding blocks the effects of these hormones in the body.

Is spironolactone a testosterone blocker?

Testosterone blockers In the United States, the most common medication against testosterone is spironolactone. Spironolactone pills may block the effects of testosterone and also reduce the levels in the blood. With the fall in testosterone level, you may notice breast tenderness.