What does ns1ag positive mean?

What does ns1ag positive mean?

A positive NS1 test result confirms dengue virus infection without providing serotype information. A negative NS1 test result does not rule out infection. People with negative NS1 results should be tested for the presence of dengue IgM antibodies to determine possible recent dengue exposure.

What is the amount of sensibility of NS1 in primary infection?

In primary infections, the InBios NS1 kit demonstrated a higher sensitivity (98.8%) than in secondary infections (83.5%).

Is dengue Duo test accurate?

The current evaluation of the SD Dengue Duo NS1/IgM shows that this assay has a sensitivity of 88.65% (95% CI: 84.04–93.26), a specificity of 98.75% (95% CI: 96.26–100) with an assay efficiency of 91.70%.

What is normal value of NS1 antigen?

An NS1 Ag level varies from 0.5-2 μg/ml in acute-phase serum samples, to less than 0.04 μg/ml in convalescent phase serum [11].

Can NS1 be false negative?

False-negative NS1 tests have been reported in dengue serotypes 2 and 4 infections. NS1 tests are also reported to be less sensitive in secondary dengue. Little is known about the causes of false-positive NS1 tests, except for possible cross-reactivity with other flaviviruses and possibly, cytomegalovirus (CMV).

What is the normal range of dengue?

Reference Range: Dengue Fever Virus Antibody, IgG 1.64 IV or less: Negative – No significant level of detectable dengue fever virus IgG antibody. 1.65-2.84 IV: Equivocal – Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.

Is dengue NS1 curable?

There is no dengue cure available. The disease is usually self-limiting and goes away after two weeks in a typical infection. Some people, however, may become critical and have severe internal bleeding or dengue haemorrhagic fever.

How do you treat an NS1 antigen test?

The NS1 antigen test is the most effective for early diagnosis of dengue infection. The main focus of treatment is to ensure that the patient gets adequate hydration. Acetaminophen (paracetamol) is used to manage the fever. If the symptoms are treated properly, the patient should recover in around two weeks.

Is dengue NS1 severe?

NS1 antigen levels of >48.49 (Panbio units) at the time of admission were associated with a specificity of 80.25% (73.27 to 86.08%) and a sensitivity of 41.67 % (22.11 to 63.36%) of developing shock.