What are the side effects of GCSF injections?
What side effects may I notice from receiving this medicine?
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue.
- back pain.
- dizziness or feeling faint.
- fever.
- pain, redness, or irritation at site where injected.
- pinpoint red spots on the skin.
- shortness of breath or breathing problems.
How safe is filgrastim?
Neupogen® is safe for most adults, but should not be taken by people who have known hypersensitivity to E. coli-derived proteins, filgrastim, or any component of filgrastim. Children and pregnant women should take Neupogen® with caution.
How long do GCSF injections take to work?
This usually takes 5 to 7 days, although it can be longer. Long-acting G-CSF is given as a single injection the day after chemotherapy has completed. If you are having G-CSF before a stem cell transplant, you usually have your first injection 4 to 6 days before your stem cells are going to be collected.
Can G-CSF cause fever?
G-CSF causes low-grade fever that is ameliorated by nonsteroidal anti-inflammatory drugs (NSAIDs), suggesting the activation of arachidonic acid (AA) cascade. How G-CSF regulated this reaction was assessed.
Can filgrastim cause leukemia?
This medicine may cause blood or bone marrow problems (eg, myelodysplastic syndrome, acute myeloid leukemia) in patients with breast or lung cancer.
How long do you take filgrastim for?
If you are using filgrastim injection products to decrease the risk of infection, decrease the time with fever, or increase the number of white blood cells during chemotherapy, you will receive your first dose of the medication at least 24 hours after you receive a dose of chemotherapy, and will continue to receive the …
When should I take filgrastim injection?
It is usually given once a day, but filgrastim injection products (Neupogen, Nivestym, Zarxio) may be given twice a day when it is used to treat severe chronic neutropenia. The length of your treatment depends on the condition that you have and how well your body responds to the medication.
How long do the effects of filgrastim last?
Neulasta is a long lasting medicine, with peak levels achieved 24 hours after injection, levels drop considerably over the first 7 days and after 14 days there is only a small amount remaining in the body.
When should filgrastim not be given?
This medication is usually given at least 24 hours after chemotherapy to stimulate the growth of new, healthy, white blood cells (WBC). Pegfilgrastim is a longer acting form of filgrastim and the manufacturer recommends that it should not be given within 14 days prior to chemotherapy.
What is filgrastim used for?
Filgrastim injection is used to treat neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in your body called a colony stimulating factor. Filgrastim helps the bone marrow to make new white blood cells.
