Is Alfaxan propofol?
Unlike propofol, alfaxalone is not associated with respiratory depression or hypotension at normal induction doses. In addition, it is the only drug approved by the FDA for the induction and maintenance of anesthesia in both dogs and cats.
What type of drug is alfaxalone?
Alfaxalone, also known as alphaxolone or alphaxalone and used under the trade name Alfaxan®, is a neuroactive steroid and general anesthetic drug used in dogs and cats. It can be used as an induction agent or for general anesthesia. Although expensive, it has some important advantages.
What schedule is Alfaxan?
Controlled Substance: ALFAXAN contains alfaxalone, a neurosteroid anesthetic and a class IV controlled substance.
How long does Alfaxan last?
This sedation usually lasts 20 to 40 minutes, depending on the drugs and dosages used in combination with alfaxalone. If general anesthesia is required, 2 to 3 mg/kg of alfaxalone (or any induction agent) can be administered intravenously after the catheter is in place.
Who makes alfaxalone?
Alfaxan Multidose IDX is marketed by Jurox PTY LTD of New South Wales, Australia, as an injectable solution. Alfaxalone is classified by the Drug Enforcement Agency as a Schedule IV controlled substance. More information: Issued by FDA Center for Veterinary Medicine.
Is Alfaxan a sedative?
INTRAMUSCULAR ALFAXALONE Butorphanol is an opioid with minimal cardiovascular effects at clinical doses and is mainly used for its sedative properties.
Why is alfaxalone controlled?
One commenter noted that controlling alfaxalone as a schedule IV controlled substance is appropriate because it could be abused in a manner similar to other schedule IV CNS depressants.
Can you give Alfaxan?
CONCLUSION. Alfaxalone administered via the intramuscular route provides rapid, dose-dependent sedation or general anaesthesia. Combining with (dex)medetomidine and an opioid will reduce dose requirements, and therefore injection volume, and will aid a smooth recovery.
Can you mix butorphanol and alfaxalone?
Alfaxalone administered IM provides rapid, dose-dependent sedation with a short duration of action. Combining with butorphanol will reduce dose requirements, an advantage in larger cats, and will assist in smoothing recovery.
Can you mix butorphanol and Alfaxalone?
Can Alfaxalone be given intramuscularly?
Although in Europe Alfaxan® is registered only for intravenous injection and not for intramuscular administration, alfaxalone can be effectively delivered by the i.m. route in both cats and dogs.
