How did my child get sickle cell trait?

Getting sickle cell trait is like getting the color of ones eyes, it is inherited from parents. Your baby inherited a normal hemoglobin gene from one parent and an “S” or sickle gene from the other parent.

Who is commonly affected more with sickle cell trait?

Risk Factors Sickle cell disease is more common in certain ethnic groups, including: People of African descent, including African-Americans (among whom 1 in 12 carries a sickle cell gene) Hispanic-Americans from Central and South America. People of Middle Eastern, Asian, Indian, and Mediterranean descent.

Can sickle cell patients go to the mountains?

Patients with sickle cell disease are at high risk of crisis in the mountains, and we advise those with intact spleens to breathe supplemental oxygen during air travel.

Does altitude affect anemia?

People living at high altitude (≥8,000 feet) are continuously exposed to lower partial pressure of oxygen, resulting in tissue hypoxia, a state of natural reduction of the HIF-PH pathway. The effect of hypoxia on endogenous EPO production and subsequent erythropoiesis may affect the prevalence of anemia.

Which parent carries the sickle cell trait?

To inherit sickle cell trait, a child must get the sickle (S) gene from one parent and a normal gene (A) from the other parent (Picture 1). If a child inherits the sickle (S) gene from one parent and a sickle (S) or other abnormal hemoglobin gene* from the other parent, the child will have sickle cell disease.

Does sickle cell trait cause iron deficiency?

The reduced frequency of iron deficiency anaemia in sickle cell trait may be explained by increased iron absorption, or alternatively by reduced iron requirements and a lower risk of discrepancy between iron supply and demand.

Does High Altitude affect sickle cell trait?

High Altitude Participation. Due to the lack of oxygen in high altitudes, athletes with sickle cell trait take a higher risk when participating in this environment. Splenic infarction can occur in athletes with sickle cell trait, particularly at high altitudes.

Can the sickle cell trait turn into the disease?

Sickle cell trait is NOT a disease and will never turn into a disease. People with sickle cell trait usually do not have any health problems. However, under extreme conditions a person with sickle cell trait can experience some of the same problems as a person who has sickle cell disease.

Is High Altitude bad for sickle cell?

How does high altitude affect sickle cell anemia?

Is it healthier to live at high altitude?

Living at higher altitudes seems to be associated with lower mortality from cardiovascular diseases, stroke and certain types of cancer. In contrast mortality from COPD and probably also from lower respiratory tract infections seems to be increased.

Can a child have sickle cell trait if neither parent has it?

Your child would have to inherit two sickle cell genes to have sickle cell disease. So if your child’s father does not have the sickle cell gene, your child can’t get sickle cell disease. But if your child’s father has the sickle cell gene, your child can get sickle cell disease.